Haematology

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Chemical Pathology
Chemical Pathology & Endocrinology is state of the art department with TLA (Total Lab Automation) providing diagnostic facilities round the clock backed up with stringent QC (Quality Control) Competent consultants and staff are working round the clock for the provision of diagnostic facilities in accordance with ISO 15189 standards meeting the international levels. Endocrine clinic has the capabilities of latest diagnostic modalities equipped to perform various dynamic function tests....
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FMSL
Forensic Medical Sciences Laboratory (FMSL) was established at AFIP in 2012. This laboratory comprises two sections namely: Forensic Toxicology and Forensic DNA. FMSL was established to provide a centralized facility for consistent, timely and quality forensic laboratory investigations including toxicology and DNA in military setting. Toxicology section is equipped with the latest state of the art technology for the initial screening and subsequent confirmation of multiple toxicology paramete...
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Haematology
Department of Haematology provides a comprehensive, integrated and patient centered services for the diagnosis and management of benign and malignant haematological conditions for inpatients and outpatients. These include anaemias, haemoglobinopathies, coagulation disorders, leukaemias and lymphomas. Department is committed to the provision of a quality laboratory and clinical service. Department is divided into the following sections: i. Routine Haematology ii. Bone marrow Pathology iii. ...
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Histopathology
Histopathology Department of AFIP Rawalpindi is one of the oldest histopathology centers in the country. This department deals with cases of morbid anatomy, cytological specimens and autopsy specimens for histopathology with almost workload of 30,000 biopsy specimens, 4,000 FNAC/Cytology specimens and 150 autopsy specimens annually. Histopathology Department is recognized by CPSP Pakistan and PMDC for post-graduate training purposes including FCPS and PhD of the highest quality. A large numbe...
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Immunology
With the advent of new millennium, Immunology services at AFIP have advanced at a fast pace. Thanks to growing awareness about the availability of these services by the clinicians as well as the emergence of centres like AFBMTC. DNA based HLA typing procedure received a huge impetus with the start of bone marrow transplant services. Workload and work pattern necessitated procurement of many new reagents and instruments. These acquisitions ranged from small gadgets like pH meter, nephelometer, CO...
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Microbiology
Department of Microbiology is well known for its efficient and reliable microbiological services to individual patients and the hospitals. This department deals with all kinds of routine and specialized microbiological testing of clinical specimens with supreme professionalism, dedication and commitment. Latest bacterial identification biochemical panels identify the isolates and complete set of respective drug sensitivity is performed. Culture and processing of most valuable sample of blood...
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Molecular Pathology
Department of Molecular Medicine at Armed Forces Institute of Pathology was established by Maj Gen (R) Suhaib Ahmed, Professor of Haematology in 1984, as a single room laboratory. It started with conventional PCR for beta thalassmeia. Presently it provides facilities for molecular genetic testing for both benign and malignant conditions. Well qualified and experienced laboratory directors, scientific officers and technicians here are leaders in the field of molecular testing in Pakistan, who con...
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NMC
Nuclear Medical Centre AFIP is state of the art centre for nuclear medicine, molecular imaging & radionuclide therapy, which is committed to improve health through excellence in image-based patient care, research and education. Department is ISO 9001 certified and is functioning under license for use of radionuclides from Pakistan Nuclear Regulatory Authority (PNRA). In General Nuclear Medicine and Cardiology, the radioactive pharmaceuticals with specific functions throughout the body are admini...
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Virology
Virology is a rapidly expanding field of medicine, and Virology Department in AFIP plays a very vital role in assisting physicians about the diagnosis of viral infections. This department provides specialized tertiary care diagnostic facilities in the field of Medical Virology to both Armed Forces personnel and civilians. We have a wide variety of serological, immunofluorescence and PCR-based tests. Serology section includes important parameters like hepatitis screening, complete Hepatitis B Vi...
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Department of Haematology provides a comprehensive, integrated and patient centered services for the diagnosis and management of benign and malignant haematological conditions for inpatients and outpatients. These include anaemias, haemoglobinopathies, coagulation disorders, leukaemias and lymphomas. Department is committed to the provision of a quality laboratory and clinical service.

Department is divided into the following sections:
i. Routine Haematology
ii. Bone marrow Pathology
iii. Coagulation studies
iv. Haemoglobin studies
v. Molecular biology
vi. Cytogenetics and FISH

All the sections have state of the art equipments unparalleled to any national institution. These include:
i. Sysmex XN series fully automated Haematology Analyzer with Autostainer
ii. Sysmex CS-5100, CA-1600 and PFA-200 coagulation analyzers
iii. Vacuette SRS 20/11 automated ESR system
iv. Platelet aggregometer
v. HPLC BioRad D10
vi. Sebia MiniCap Haemoglobin electrophoresis system
vii. Cytovision for routine and FISH cytogenetics
viii. Metasystems fully automated cytogenetics and FISH system
ix. Olympus 18 head teaching microscope with camera, software and display system
x. Applied biosystems real time PCR systems
xi. Applied biosystems genetic analyzers
xii. Illumina Next Generation Sequencing system

Sections of Molecular Biology and Cytogenetics are extending facilities, most of which are not available at any other laboratory, at very nominal rates. Section of Molecular Biology started with conventional PCR for beta thalassemia in 1994. Presently it provides facilities for molecular genetic testing for both benign and malignant conditions. Well qualified and experienced laboratory directors, scientific officers and technicians here are leaders in the field of molecular testing in Pakistan, who continually strive to develop new test methods that improve patient care. They continually work to improve assays by increasing the number of mutations detected and decreasing turnaround time.

Department also has a long and rich tradition of excellence in research and training in Haematology at both undergraduate and post-graduate level.

The faculty and staff are nationally and internationally renowned leaders in their areas of research and expertise, and are committed to advancing the science and practice of Hematology.
Distinctive Competence
1. Thrombophilia screening
2. Platelet aggregation studies
3. Factor assays
4. Inhibitor screening and levels
5.Cytochemical staining of bone marrow aspiration smears
6. Gel and capillary electrophoresis along with HPLC for diagnosis of haemoglobinopathies
7. Routine cytogenetics
8. FISH for 16 different chromosomal and genetic abnormalities
9.Detection of genetic abnormalities by molecular techniques including conventional PCR, real time PCR, sanger sequencing and fragment analysis.
Facilities
  • Blood & Bone marrow examination
  • Coagulation studies
  • Platelet function tests
  • Haemoglobin studies
  • Thrombophilia studies
  • Cytogenetics
  • Molecular genetics
Latest Publications
1.     Khurshid A, Khan SA, Hussain CA, Hussain A, Malik HS (2017) BRAF V600E mutation in hairy cell leukaemia A single center descriptive cross sectional study. HematolTransfusInt J 5(4): 00124. DOI: 10.15406/htij.2017.05.00124

3.     Ali J, Khan S, Rauf S, Ayyub M, Ali N, Afridi NK. Comparative analysis of fluorescence in situ hybridization and real time polymerase chain reaction in diagnosis of chronic myeloid leukemia. J Coll Physicians Surg Pak 2017; 27: 26-9.

5.     Khan A, Ayyub M, Ahmed S, Altaf CH, Malik HS (2016) Frequency of Three Different Gene Mutations (TEL-AML1, E2A-PBX1 and MLL-AF4) In Acute Lymphoblastic Leukaemia. HematolTransfusInt J 2016 ; 2(4): 00045. DOI: 10.15406/ htij.2016.02.00045

2.     Hussain A, Ahmed S, Ali N, S Mailk H, Anees M, Chuahdry AH, Ahmed P. Rare β-Globin Gene Mutations in Pakistan. Hemoglobin. 2017 Mar;41(2):100-103. doi: 10.1080/03630269.2017.1339612. Epub 2017 Jul 3.

4.     Rafia M, Altaf C, Parvez A, Ahmed KS, Saeed MH. Myelodysplastic syndrome in Pakistan - clinicohaematological characteristics, cytogenetic profile and risk stratification. Turk J Haematol. 2017 Jun 7 doi: 10.4274/tjh.2017.0130.



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